The Waters 2424 ELS (ELS) Detector was designed to provide a critical balance in mind to deliver good sensitivity of semi-volatile components and low peak dispersion.  Active nebulizer heating and cooling for method optimization and rapid stabilization  60° scatter angle detection to minimize stray light and optics polarization for long-term optimal sensitivity  Optimal energy output for improved bench-to-bench repeatability The Waters 2424 ELS Detector (ELSD), with its compact and innovative design, offers near-universal detection of non-volatile and semi-volatile sample components. The 2424 ELS Detector is compatible with both isocratic and gradient separations and has nebulizer options to cover a wide range of analytical and microbore flow rates. By adding the or-thogonality of ELSD to your detection strategy, you increase peak detection confidence across a wide application space. Evaporative light scattering (ELS) detection works by nebulizing the solvent flow from a liquid chromatography (LC) system and entraining the resultant droplets in a gas stream. Mobile phase is then evaporated from the droplets. When an analyte is less volatile than the mobile phase, it remains in the gas stream as a "dry" solute particle and flows to the ELS detector. Once there, the particles scatter the light beam. The amount of scattered light is measured and bears a relationship to the concentration of material eluting. The 2424 ELS detector is compatible with virtually all modes of chromatography including flow injection analysis.